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2021
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Multi-Functional Degraders
(1)
OPN-51107
(17)
OPN-6602
(3)
OPN-7486
(5)
OPN-TEAD
(2)
Zavabresib (OPN-2853)
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2025
(3)
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October 15, 2021
Publication
Inhibition of Bromodomain and Extra Terminal (BET) Domain Activity Modulates the IL-23R/IL-17 Axis and Suppresses Acute Graft- Versus-Host Disease
AUTHORS
Snyder, et al
Programs
OPN-51107
,
Zavabresib (OPN-2853)
https://doi.org/10.3389/fonc.2021.760789
May 20, 2021
Poster
Phase 1b/2a Study of PLX2853, a Small Molecule BET Inhibitor, in Subjects with Advanced Solid Tumors and Lymphoma
AUTHORS
Gordon, et al
Programs
Zavabresib (OPN-2853)
Download PDF
January 28, 2021
Publication
A novel combination regimen of BET and FLT3 inhibition for FLT3-ITD acute myeloid leukemia
AUTHORS
Lee, et al
Programs
OPN-51107
https://doi.org/10.3324/haematol.2020.247346